Anatomical Pathology -- Insight

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The Journal of Clinical and Experimental Pathology (ISSN: 2161-0681) deals with research on infectious disorders associated with immune system and immunological disorders, infectious diseases, treatment of infectious diseases, infectious medicine, epidemiology, diagnostic tests of infectious diseases, infection control, pathophysiology, clinical pathology , preventive medicine. Clinical Pathology deals with patient care, diagnostic services, novel treatments and research on immune infections. Journal of Clinical & Experimental Pathology covers all areas of clinical and experimental pathology. Articles such as research papers, review articles, commentaries and short communications leading to the development of Journal of clinical and experimental pathology.

Anatomical pathology (Commonwealth) or Anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. The primary role of anatomic pathology is to identify abnormalities that can help to diagnose disease and manage treatment. Although one of the frequent uses of anatomic pathology is to help identify and manage various types of tumors or cancers, it is also valuable in evaluating other conditions like kidney and liver diseases, autoimmune disorders, and infections.

There are two main subdivisions within anatomic pathology: Histopathology, which involves examination of intact tissue from biopsy or surgery under the microscope. This is often aided by the use of special staining techniques and other associated tests, such as using antibodies to identify different components of the tissue. Cytopathology (cytology) is the examination of a single cell or small group of cells from scraping or aspiration of fluid or tissue under the microscope. A common cytology test is the cervical Pap smear. Technologists often screen preparations and report results but, in many cases, the pathologist gives the definitive diagnosis to the healthcare practitioner. Anatomical pathology is also divided into subspecialties like surgical pathology (breast, gynecological, endocrine, gastrointestinal, GU, soft tissue, head and neck, dermatopathology), neuropathology, hematopathology, cytopathology, and forensic pathology.

Anatomic pathologists are also involved in performing post-mortem examinations (autopsies). An autopsy may be performed after a person has died of an illness that could not, for whatever reason, be properly or fully diagnosed before death. Anatomic pathologists usually work in hospitals, investigating the effects of disease on the human body via autopsies and microscopic examination of tissues, cells, and other specimens. Medical laboratory directors are responsible for the sophisticated laboratory tests on samples of tissues or fluids and the quality and accuracy of the tests. The procedures used in anatomic pathology include gross examination, histopathology, immunohistochemistry, in situ hybridization, cytopathology, electron microscopy, tissue cytogenetics and flow immunophenotyping.

In addition to the diagnosis, the surgical pathologist provides information about the grade of malignancy, adequacy of excision, and other important parameters which will contribute to the treatment of the patient. Slide review and consultation is an important aspect of surgical pathology, confirming the correct diagnosis, and ensuring uniformity of diagnosis and nomenclature at our institution. The exponential growth in knowledge, and the incorporation of increasingly sophisticated techniques, has made sub specialization an essential part of cutting edge surgical pathology as practiced at UCLA.

Although performed in a laboratory setting, anatomic pathology is not simply a “lab test” in the traditional sense. Rather, it is a professional interpretation of a tissue specimen by a specialized physician who integrates data from the gross and microscopic examination of tissue, specialized testing, and clinical data to arrive at a diagnosis. Perhaps the best-known example of this is a biopsy to determine if a patient has cancer. “No patient has cancer until a pathologist says the patient has cancer”, and this is true in the vast majority of cases – most surgeons, oncologists, and radiation therapists won’t treat a patient without a diagnosis from a pathologist.

On the occasion of its 10 years, Successful Journey, Journal of Clinical and Experimental Pathology decided to provide a partial waiver on its article processing charges to promote quality research from across the nations of the globe to encourage the latest research in the field of Infections, Diseases and Medicine. Journal of Clinical and Experimental Pathology also planning to release a special issue on its new approaches.

Regards,

Robert Solomon

Editorial office

Journal of Clinical and Experimental Pathology

E-mail: pathol@eclinicalsci.com

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