Biomolecular research and use of biomolecules and different technologies like Nano-Technology in the treatment of various forms of Carcinoma like Basal cell carcinoma, Squamous cell carcinoma, Renal cell carcinoma, Invasive ductal carcinoma, Adenoma carcinoma. Proteins and membrane lipids interact in a number of ways to provide a stable membrane environment for proteins to encapsulate and specific roles in intricate and well-regulated processes. Functions of proteins advancements in both experimentation and computation have gathered to investigate the lipid protein interactions, an area that is quickly increasing. A database of high-resolution membrane protein structures is developing experimentally, identifying examining the diverse lipid compositions of different membranes challenging lipid-protein interaction time and length scales. More chances exist to relate protein interactions to. It functions with a range of proteins. Computational, More precise membrane models offer a thorough understanding of interactions between lipids and proteins, increasing simulated duplication and experimental findings for the verification of experimental results, and co-interpretation. All life depends on the cell membrane, which surrounds both the internal organelle and the entire cell. Depending on the cell type and membrane location, they are made up of a complicated mixture of lipids and proteins with lateral architectures that have not yet been fully explained. The movement of nutrients, metabolites, energy, and information can all be tightly controlled by cell membranes. Although historically these functions have been predominantly attributed to membrane proteins, there is mounting evidence that lipid-protein interactions play a significant role in the membrane binding process. The lipid component of the developing body and an important pharmacological target, membrane proteins are a direct result of this. The exterior and interior lipids of the cell membrane are organised from tail to tail. The three main classes of lipids are glycerophospholipids, sphingolipids, and sterols. Lipid-protein interactions, which alter the physical characteristics of the membrane and alter the membrane structure on a microscopic level, are far from highly specialised interactions between particular lipids that directly affect the selective binding sites of proteins. It is categorised as having lengths ranging up to general interactions, such as when two membrane proteins. By studying X-ray crystal structures, it is possible to discover the structural characteristics of the lipid binding site. By removing membrane proteins from the lipid bilayer and solubilizing them using detergents, high resolution structures for X-ray crystallography can be generated. When proteins are purified and crystallised using detergents, naturally occurring lipids linked with the proteins are frequently lost or crystallised and lost together. Due to the way it is structured, it might not be easy to distinguish. X-ray crystallography has been used to identify several membrane proteins that were strongly attached to lipids and survived the solubilisation and purification processes, despite the numerous difficulties that membrane proteins present. Through Mass Spectrometry (MS) research, natural lipid species that are closely connected to membrane proteins can be quantitatively analysed and identified. For resistance to the electrospray ionisation process and gas phase, the membrane protein complex was solubilized in a non-ionic detergent for this investigation. This method has been used to gather data on lipid selectivity, binding stoichiometry, and the potential function of lipids in protein processes from a variety of transporters and other membrane proteins. We can examine the thermodynamics of lipid binding to membrane proteins and shed insight on the mechanisms of molecular recognition between lipids and proteins.