Malignancy of Lymphoma

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The Journal of Clinical and Experimental Pathology (ISSN: 2161-0681) deals with research on infectious disorders associated with immune system and immunological disorders, infectious diseases, treatment of infectious diseases, infectious medicine, epidemiology, diagnostic tests of infectious diseases, infection control, pathophysiology, clinical pathology , preventive medicine. Clinical Pathology deals with patient care, diagnostic services, novel treatments and research on immune infections. Journal of Clinical & Experimental Pathology covers all areas of clinical and experimental pathology. Articles such as research papers, review articles, commentaries and short communications leading to the development of Journal of clinical and experimental pathology.

Lymphoma is cancer that begins in infection-fighting cells of the immune system, called lymphocytes. These cells are in the lymph nodes, spleen, thymus, bone marrow, and other parts of the body. When you have lymphoma, lymphocytes change and grow out of control. There are two main types of lymphoma and they are Non-Hodgkin: Most people with lymphoma have this type and Hodgkin. Non-Hodgkin and Hodgkin lymphoma involve different types of lymphocyte cells. Every type of lymphoma grows at a different rate and responds differently to treatment. Lymphoma is very treatable, and the outlook can vary depending on the type of lymphoma and its stage. Lymphoma starts in infection-fighting lymphocytes. As this type of cancer is present in the lymph system, it can quickly metastasize, or spread, to different tissues and organs throughout the body. People of any age can develop lymphoma, but it is among the most common causes of cancer in children and young adults aged 15–24 years. It is often treatable.

Lymphoma may not always cause symptoms in its early stages. Instead, a doctor may discover enlarged lymph nodes during a physical examination. These may feel like small, soft nodules under the skin. A person may feel the lymph nodes in the neck, upper chest, armpit, stomach and groin. Likewise, many of the symptoms of early lymphoma are not specific. That makes them easy to overlook. These common early symptoms of lymphoma include: bone pain, cough, fatigue, enlarged spleen, fever, night sweats, pain when drinking alcohol, itchy rash, rash in skin folds, shortness of breath, skin itching, stomach pain and unexplained weight loss. Because the symptoms of lymphoma are often easily overlooked, it can be difficult to detect and then diagnose it in an early stage. It’s important to know how the symptoms may begin to change as the cancer worsens.

The risk factors of Non-Hodgkin’s Lymphoma include immunodeficiency, autoimmune disease, age, sex, ethnicity, infection and chemical, radiation exposure and body size. The risk factors of Hodgkin’s Lymphoma include age, sex, family history, infectious mononucleosis, affluence and immunodeficiency.

A biopsy typically is taken if a doctor suspects lymphoma. This involves removing cells from an enlarged lymph node. A doctor known as a hematopathologist will examine the cells to determine if lymphoma cells are present and what cell type they are. If the hematopathologist detects lymphoma cells, further testing can identify how far the cancer has spread. These tests can include a chest X-ray, blood testing, or testing nearby lymph nodes or tissues. Imaging scans, such as a computed tomography (CT) or magnetic resonance imaging (MRI) scans may also identify additional tumors or enlarged lymph nodes.

The treatment you get depends on what type of lymphoma you have and its stage. The main treatments for non-Hodgkin lymphoma are chemotherapy, which uses drugs to kill cancer cells, radiation therapy, which uses high-energy rays to destroy cancer cells, immunotherapy, which uses your body's immune system to attack cancer cells, targeted therapy that targets aspects of lymphoma cells to curb their growth. The main treatments for Hodgkin lymphoma are chemotherapy, radiation therapy and immunotherapy.

On the occasion of its 10 years, Successful Journey, Journal of Clinical and Experimental Pathology decided to provide a partial waiver on its article processing charges to promote quality research from across the nations of the globe to encourage the latest research in the field of Infections, Diseases and Medicine. Journal of Clinical and Experimental Pathology also planning to release a special issue on its new approaches.

Regards,

Robert Solomon

Editorial office

Journal of Clinical and Experimental Pathology

E-mail: pathol@eclinicalsci.com

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