The Journal of Clinical and Experimental Pathology (ISSN: 2161-0681) deals with research on infectious disorders associated with immune system and immunological disorders, infectious diseases, treatment of infectious diseases, infectious medicine, epidemiology, diagnostic tests of infectious diseases, infection control, pathophysiology, clinical pathology , preventive medicine. Clinical Pathology deals with patient care, diagnostic services, novel treatments and research on immune infections. Journal of Clinical & Experimental Pathology covers all areas of clinical and experimental pathology. Articles such as research papers, review articles, commentaries and short communications leading to the development of Journal of clinical and experimental pathology.

Leukemia, also spelled leukaemia, is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. WBCs are a vital part of your immune system. They protect your body from invasion by bacteria, viruses, and fungi, as well as from abnormal cells and other foreign substances. In leukemia, the WBCs don’t function like normal WBCs. They can also divide too quickly and eventually crowd out normal cells. WBCs are mostly produced in the bone marrow, but certain types of WBCs are also made in the lymph nodes, spleen, and thymus gland. Once formed, WBCs circulate throughout your body in your blood and lymph (fluid that circulates through the lymphatic system), concentrating in the lymph nodes and spleen.

Different types of leukemia can cause different problems. You might not notice any signs in the early stages of some forms. When you do have symptoms, they may include: weakness or fatigue, bruising or bleeding easily, fever or chills, infections that are severe or keep coming back, pain in your bones or joints, headaches, vomiting, seizures, weight loss, night sweats, shortness of breath, swollen lymph nodes or organs like your spleen.

The causes of leukemia aren’t known. However, several factors have been identified which may increase your risk. These include: a family history of leukemia, smoking, which increases your risk of developing acute myeloid leukemia (AML), genetic disorders such as Down syndrome, blood disorders, such as myelodysplastic syndrome, which is sometimes called “preleukemia”, previous treatment for cancer with chemotherapy or radiation, exposure to high levels of radiation and exposure to chemicals such as benzene.

Diagnosis of Leukemia includes Blood tests: A complete blood count (CBC) looks at the number and maturity of different types of blood cells. A blood smear looks for unusual or immature cells. Bone marrow biopsy: This test involves marrow taken from your pelvic bone with a long needle. It can tell your doctor what kind of leukemia you have and how severe it is. Spinal tap: This involves fluid from your spinal cord. It can tell your doctor whether the leukemia has spread. Imaging tests: Things like CT, MRI, and PET scans can spot signs of leukemia.

A number of other tests can be used to assess the progression of the disease such as Flow cytometry examines the DNA of the cancer cells and determines their growth rate, liver function tests show whether leukemia cells are affecting or invading the liver, lumbar puncture is performed by inserting a thin needle between the vertebrae of your lower back which allows your doctor to collect spinal fluid and determine if the cancer has spread to the central nervous system, imaging tests, such as X-rays, ultrasounds, and CT scans, help doctors look for any damage to other organs that’s caused by the leukemia. Treatment includes chemotherapy, radiation therapy, stem cell transplantation, biological or immune therapy and targeted therapy.

On the occasion of its 10 years, Successful Journey, Journal of Clinical and Experimental Pathology decided to provide a partial waiver on its article processing charges to promote quality research from across the nations of the globe to encourage the latest research in the field of Infections, Diseases and Medicine. Journal of Clinical and Experimental Pathology also planning to release a special issue on its new approaches.

Regards,

Robert Solomon

Editorial office

Journal of Clinical and Experimental Pathology

E-mail: pathol@eclinicalsci.com

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